CourseNuclear Engineering & Nuclear Fuel Cycle Technologies Applications open

Course in Radiation Ethics in Animal Research

Online 300-hour course in radiation ethics in animal research. 6 modules covering Directive 2010/63/EU (protection of animals used for scientific purposes), Royal Decree 53/2013 (basic rules for the protection of animals used in experimentation) and NC3Rs Experimental Design Assistant. Assigned tutor and open enrolment.

Duration300 h
ModeOnline
Start datesSet by the faculty
AwardSEIUM Institute certificate
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Learning outcomes

What you will be able to do

01

Describe the uses of radiation in animal research.

02

Apply the 3Rs principle to experimental design.

03

Evaluate procedures according to severity and animal welfare criteria.

04

Apply radiation protection to staff and the animal facility environment.

05

Interpret the European and Spanish regulatory framework for animal experimentation.

06

Assess the role of ethics committees and oversight.

07

Develop an ethical research project involving radiation in animals.

Profile

Who it's for

  • Radiobiology researcher wishing to specialise in radiation ethics in animal research.
  • Animal facility veterinarian wishing to specialise in radiation ethics in animal research.
  • Radiation protection supervisor wishing to specialise in radiation ethics in animal research.
  • Member of an animal experimentation ethics committee wishing to specialise in radiation ethics in animal research.
  • Preclinical imaging technician wishing to specialise in radiation ethics in animal research.
  • Animal welfare officer wishing to specialise in radiation ethics in animal research.
  • Graduates in engineering or science seeking to enter biomedical research.
Standards & tools

What you'll work with

  • Directive 2010/63/EU (protection of animals used for scientific purposes)
  • Royal Decree 53/2013 (basic rules for the protection of animals used in experimentation)
  • Directive 2013/59/Euratom (basic safety standards)
  • Royal Decree 1029/2022 (protection of health against ionising radiation)
  • ARRIVE 2.0 Guidelines
  • European Convention ETS 123 (protection of vertebrate animals used for experimental and other scientific purposes)
  • ICRP 108 (reference animals and plants)
Syllabus

6 modules · 300 h

  1. 1.1Uses of radiation in animal biomedical research
  2. 1.2Preclinical imaging and experimental radiotherapy
  3. 1.3Isotope labelling and metabolic studies
  4. 1.4Irradiation of samples and animals
  5. 1.5Legal framework for the protection of animals used in experimentation
  6. 1.6Principle of replacement, reduction and refinement
  7. 1.7Project authorisation and authorised bodies
  8. 1.8Role of the designated veterinarian
  9. 1.9Dual framework: animal welfare and radiation protection
  10. 1.10Exercise: identify the obligations of a project
  1. 2.1Scientific question and the need for an animal model
  2. 2.2Sample size calculation
  3. 2.3Reducing animal numbers through design
  4. 2.4In vitro and in silico alternatives
  5. 2.5Choice of species and strain
  6. 2.6Minimum necessary radiation dose
  7. 2.7Fractionation and irradiation protocols
  8. 2.8Humane endpoints
  9. 2.9Protocol registration and publication
  10. 2.10Practice: critically review a design
  1. 3.1Housing and environmental enrichment
  2. 3.2Assessment of pain and distress
  3. 3.3Anaesthesia, analgesia and sedation
  4. 3.4Handling during image acquisition
  5. 3.5Restraint and associated stress
  6. 3.6Signs of radiotoxicity and clinical monitoring
  7. 3.7Humane euthanasia criteria
  8. 3.8Classification of procedure severity
  9. 3.9Recording observations and traceability
  10. 3.10Practice: clinical monitoring sheet
  1. 4.1Zoning of the animal facility with isotopes
  2. 4.2Shielding and laboratory equipment
  3. 4.3Handling radiopharmaceuticals in small volumes
  4. 4.4Contamination from excreta and bedding
  5. 4.5Management of radioactive biological waste
  6. 4.6Carcasses and tissues with residual activity
  7. 4.7Dosimetry of research staff
  8. 4.8Written procedures and training
  9. 4.9Response to spills and contamination
  10. 4.10Practice: laboratory working procedure
  1. 5.1Deliberation on harm to the animal and expected benefit
  2. 5.2Documented harm and benefit analysis
  3. 5.3Ethics committee: operation and criteria
  4. 5.4Public transparency and communication of research
  5. 5.5Pressure to publish and its effect on design
  6. 5.6Reuse of data and animals
  7. 5.7Mandatory training for research staff
  8. 5.8Common inspections and non-conformities
  9. 5.9Culture of responsibility within the group
  10. 5.10Practice: ethical opinion on a real project
  1. 6.1Choice of scientific question
  2. 6.2Justification of the animal model and alternatives considered
  3. 6.3Experimental design and sample size
  4. 6.4Irradiation and imaging protocol
  5. 6.5Welfare plan and endpoints
  6. 6.6Laboratory radiation protection plan
  7. 6.7Waste management
  8. 6.8Harm and benefit analysis
  9. 6.9Project report for the committee
  10. 6.10Defence of the project
Methodology, software & labs

How you'll learn

100% online training on the SEIUM campus, with downloadable material, recorded classes and an assigned technical tutor. There are no fixed timetables: students progress at their own pace within the intake, which makes it possible to combine the programme with work.

Each module combines theory, guided reading of the original standard and applied exercises. The software used is NC3Rs Experimental Design Assistant, GraphPad Prism, IDAC-Dose, R, in free, academic or trial versions. Practical work is based on real cases: reviewing a procedure before an authorised body, calculating doses in animal models, and designing experiments applying the 3Rs criteria. Assessment is continuous across modules, plus the final integrative project.

Accreditable laboratories(EN ISO/IEC 17025) with a rotor test rig, EMC/Lightning pre-compliance, HIL/SIL, vibration/acoustics.
Evidence-oriented Master's Thesis:safety case, test plan, compliance dossier and operational limits.
Industry mentoring:lecturers with experience in training, , eVTOL/UAM and flight test.
Flexible format(hybrid/online), international cohorts and support from SEIUM Career Services.
Ethics and safety:safety-by-design approach, cyber-OT, DIH and compliance as core pillars.
Capstone project

Build it end to end

Your final project follows the real engineering workflow, step by step, reviewed by your tutor.

Choice of scientific question

Describe the uses of radiation in animal research.

Justification of the animal model and alternatives considered

Apply the 3Rs principle to experimental design.

Experimental design and sample size

Evaluate procedures according to severity and animal welfare criteria.

Irradiation and imaging protocol

Apply radiation protection to staff and the animal facility environment.

Welfare plan and endpoints

Interpret the European and Spanish regulatory framework for animal experimentation.

Career opportunities

Where this takes you

Radiobiology researcherAnimal facility veterinarianRadiation protection supervisorMember of an animal experimentation ethics committeePreclinical imaging technicianAnimal welfare officer
Admissions & scholarships

Requirements

  • No prior degree is required.
  • Internet connection and a computer capable of running the programme's software.
  • Sufficient level of Spanish to follow technical regulatory texts.

Ready to start?

Send your application today. Our admissions team replies within 72 hours with your study plan and funding options.

FAQ

Frequently asked questions

The programme consists of 300 hours in total, spread over 3 to 5 months. That is an average of 10 to 15 hours per week, compatible with full-time work.

You will work with NC3Rs Experimental Design Assistant, GraphPad Prism, IDAC-Dose and R. Free, academic or trial versions are used, and the tutor will indicate the free alternative where one exists.

A SEIUM own diploma upon passing the continuous assessment and the integrative project. It is in-house training, not an official title issued by the Ministry.

Yes. Modules passed in a course or postgraduate diploma in the same area are credited towards the advanced programme. Check the credit transfer policy when you enrol.

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